KMID : 1101420160480030225
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Korean Journal of Clinical Laboratory Science 2016 Volume.48 No. 3 p.225 ~ p.229
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Diagnosis for Latent Tuberculosis Infection in College Students
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Yook Keun-Dol
Yang Byoung-Seon
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Abstract
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Tuberculosis (TB) is caused by a chronic infectious agent known as Mycobacterium tuberculosis. It is transmitted in airborne particles, called droplet nuclei which was generated by cough, sneeze, shout, or sing of persons who have TB disease. Most infections of TB do not have symptoms, well known as latent tuberculosis infection (LTBI). However, about 10% of LTBI progress to active disease a one or two years after infection. To investigate the LTBI rate of college students who were in contacted with TB patients, we performed chest X-ray, tuberculin skin test (TST) and Interferon-gamma release assay (IGRA) to 74 college students. At a results, 65 students were showed negative and 9 students positive results at chest X-ray and 1st TST test. When confirmed the 65 students who were showed negative by 2st TST, the results showed correctly. But, 9 students who were showed positive results on chest X-ray and 1st TST by IGRA, the only 3 students (4.05%) showed positive results. In conclusion, the LTBI rate in this study showed 4.05% (3/74) and we suggest to investigate other students LTBI rate for decreasing tuberculosis.
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KEYWORD
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Mycobacterium tuberculosis, latent tuberculosis infection, Tuberculin skin test, Interferon-gamma release assay
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